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How long does a Lexus IS 350 engine last?

With proper maintenance, a Lexus IS 350’s 3.5-liter V6 can reliably exceed 200,000 miles, and many owners report pushing toward 250,000 miles or more.


Engine design and reliability


Durability built into the powerplant


The IS 350 uses Lexus’s robust 3.5-liter V6, commonly found in the 2GR-FKS family in newer models. This engine is period-tested for longevity, featuring a timing chain rather than a belt, advanced variable valve timing, and durable components designed for high mileage. When well maintained, these engines are known for smooth operation over many years and miles, aided by Lexus’s precision manufacturing and quality control.


What influences how long it lasts


Several factors determine the eventual lifespan of an IS 350 engine. The following elements tend to have the biggest impact on whether the engine reaches or surpasses the 200,000-mile mark.



  • Maintenance history: Regular oil changes with the recommended synthetic oil, timely filter changes, and adherence to service intervals are crucial for long life.








In short, longevity is closely tied to how consistently the vehicle is cared for and how aggressively it’s driven over its lifetime.


Maintenance habits that maximize life


Adopting disciplined maintenance practices is the best path to a longer-lived IS 350 engine. The list below outlines actions that owners commonly find effective.



  • Follow the official maintenance schedule: Keep up with oil changes, filter replacements, and other service items at the intervals specified by Lexus, typically involving synthetic oil between visits.

  • Use recommended fuels and lubricants: Run premium unleaded fuel as advised and use OEM or high-quality filters and fluids.

  • Maintain the cooling system: Regular coolant checks and a timely coolant replacement help prevent overheating and head gasket stress.

  • Monitor and service the timing chain system as needed: While timing chains last a long time, be attentive to unusual noises or timing-related symptoms and follow the service guidance for tensioners and guides.

  • Replace spark plugs at the recommended interval: For many IS 350 engines, ignition components are designed for long service intervals (often around 90,000–120,000 miles), but follow the owner's manual.

  • Keep carbon buildup in check: Particularly with direct-injection engines, periodic valve cleaning may be advised to maintain performance and efficiency.

  • Address leaks and seal wear promptly: Oil, coolant, or fuel leaks should be repaired quickly to prevent long-term damage.

  • Maintain the transmission and driveline: Follow service intervals for transmission fluid and inspection, as drivetrain health affects overall engine longevity.


These practices, combined with attentive ownership, are the most reliable way to maximize the IS 350’s engine life and preserve performance over time.


Bottom line


Across model years, the IS 350’s 3.5-liter V6 is widely regarded as a durable engine, capable of lasting well into the 200,000-mile range with diligent maintenance. Real-world longevity depends almost entirely on adherence to maintenance schedules, driving habits, and environmental conditions.


Summary


In summary, a Lexus IS 350 can reliably reach high mileages—often 200,000 miles or more—when owners commit to regular maintenance, quality fluids and parts, and mindful driving. The engine’s design supports long life, but like any modern powertrain, longevity is earned through consistent care and timely attention to issues as they arise.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.