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How long will a 2012 Lexus RX 350 last?

With proper maintenance, a 2012 Lexus RX 350 can reliably reach 200,000 miles (about 320,000 kilometers) and many owners report hitting 250,000 miles or more. A well-kept example may even approach or exceed 300,000 miles under favorable conditions.


The lifespan of a used RX 350 depends on how well it’s cared for, where and how it’s driven, and how consistently routine maintenance is performed. The 2012 model uses a durable 3.5-liter V6 with a timing chain, and a track record of solid reliability when serviced on schedule. This article reviews what to expect, how to maximize longevity, and what issues to monitor as the vehicle ages.


Projected lifespan and what to expect


Below are typical mileage milestones drawn from owner reports and automotive reviews for RX 350s that have received regular maintenance. Individual results vary with climate, driving habits, and service history.



  • 200,000 miles (approximately 320,000 km): A common milestone for well-maintained examples, especially highway-driven vehicles.

  • 250,000 miles (about 400,000 km): A substantial portion of owners report reaching this mark with routine care and timely part replacement.

  • 300,000 miles (roughly 480,000 km) and beyond: A minority of RX 350s accomplish this, typically with meticulous upkeep and favorable operating conditions.


In broad terms, the RX 350’s drivetrain and chassis are capable of long life when owners stay disciplined about maintenance and address wear items before they fail. Regular service history often correlates with higher mileages and fewer surprises.


Maintenance that supports longevity


Maximizing the RX 350’s lifespan hinges on proactive, routine maintenance across the engine, transmission, cooling system, and safety components. The following practices are especially important as the odometer climbs.



  • Follow the manufacturer’s oil-change schedule with synthetic oil, typically every 5,000–7,500 miles depending on driving conditions and manual recommendations.

  • Schedule transmission fluid changes around the intervals recommended in the owner’s manual (often around every 60,000 miles for many Lexus models) and ensure the cooling system is in good condition to prevent transmission overheating.

  • Be aware that the 3.5L V6 uses a timing chain rather than a belt, but monitor for chain tensioner wear and address any unusual noises or warning codes early; replace the water pump and thermostat as needed during high-mileage preventative maintenance.

  • Maintain brakes, suspension, and tires; timely replacement of wear items and alignment checks help preserve safety and reduce wear on other components.

  • Keep the cooling system, radiator, hoses, and thermostat in good shape; overheating is a common cause of accelerated wear in aging cars.

  • Inspect the battery, alternator, and charging system; plan for typical battery life (roughly 4–6 years in many climates) and replace as needed.

  • Stay current with recalls and service campaigns; keep comprehensive maintenance records for resale value and reliability assessment.


Following a disciplined maintenance routine helps maximize longevity and retain resale value. The RX 350 can deliver dependable service for many years if care is consistent and comprehensive.


Common issues to watch as the car ages


As with any aging vehicle, certain components may need attention sooner rather than later. Be aware of these areas and perform proactive checks during regular service visits.



  • Transmission behavior: Some high-mileage examples report shuddering, harsh or delayed shifts; diagnostic checks and fluid/service interventions can mitigate issues.

  • Steering and suspension wear: Aging bushings, ball joints, and tie rods can affect handling and tire wear; monitor for looseness or unusual noises.

  • Electrical and sensor concerns: Wheel-speed/ABS sensors and other electronic controls can trigger warning lights; timely diagnostics help avoid worse trouble.

  • Air conditioning and cooling: Components such as the A/C compressor or cooling fans may show reduced performance with age; address promptly to maintain comfort and prevent heat-related strain.

  • Rust and underbody wear: In harsher climates, corrosion protection becomes important; treat exposed metal and inspect for rust in critical areas.


These are common themes observed in aging RX 350s, but not every vehicle will experience them. Proactive maintenance and timely repairs are key to keeping an older RX 350 on the road.


Summary


The 2012 Lexus RX 350 is generally a durable SUV whose longevity hinges on diligent maintenance, attentive driving habits, and timely replacement of wear items. With regular service, many owners see 200,000 miles or more, with a meaningful share approaching 250,000 miles and beyond. If you’re considering buying one, review full service records, plan for standard aging repairs, and budget for preventative maintenance to maximize its life and value.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.