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How many miles per gallon does a 2010 GS450h get?

The 2010 GS450h, Lexus’s hybrid variant of its midsize sedan lineup, posts about 29 miles per gallon combined in EPA tests, with roughly 25 mpg in city driving and 34 mpg on the highway. Real-world results vary based on driving style and conditions.


EPA ratings for the 2010 GS450h


Official fuel-economy data from the U.S. Environmental Protection Agency is broken down by driving cycle. The numbers below reflect the 2010 model year’s estimates for typical use.



  • City: 25 mpg

  • Highway: 34 mpg

  • Combined: 29 mpg


These figures provide a baseline for what to expect in mixed driving, with highway runs tending toward the higher end and city driving toward the lower end of the spectrum.


Understanding how the numbers translate to real-world driving


EPA ratings are based on standardized tests that simulate urban and highway conditions. Actual mileage can vary due to traffic patterns, climate control use, tire choice, and how aggressively the vehicle is driven.


Real-world mileage and variability


In everyday use, owners and reviewers typically see mpg in the high 20s during mixed urban–highway trips. Long highway drives at steady speeds can push results into the low 30s, while heavy stop-and-go city traffic often yields numbers closer to the mid-to-high 20s.


Factors that affect mpg on the GS450h


Before listing the common influences on fuel economy, it helps to know what tends to move the needle in either direction.



  • Driving style and traffic patterns (stop-and-go versus steady highway cruising)

  • Tire type, condition, and proper inflation

  • Vehicle load and roof rack usage

  • Climate control usage and outside temperatures

  • Battery state of charge and how often EV mode is engaged


In practice, brisk acceleration, excessive weight, or persistent cold starting can lower mpg, while light loads, proper tire maintenance, and moderate acceleration help maximize efficiency.


Bottom line


The 2010 GS450h offers hybrid efficiency for its class, with EPA estimates around 25 mpg city, 34 mpg highway, and about 29 mpg combined. Real-world mileage typically falls within roughly 25–32 mpg, depending on conditions and driving habits.


Summary


In brief: The 2010 Lexus GS450h targets about 29 mpg combined on EPA tests, with city and highway figures of 25 mpg and 34 mpg respectively. Actual results vary, but the hybrid powertrain generally delivers solid efficiency for a luxury midsize sedan.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.