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What is the difference between a Lexus NX 300 and a Lexus RX 350?

The RX 350 is larger, more powerful, and typically more expensive than the NX 300, which is a compact SUV focused on efficiency and city driving. The NX 300 is smaller, lighter, and usually easier to park, with lower running costs. Exact specs vary by model year and market.


This article breaks down the differences between the two models across size, performance, interior space and technology, and price, so you can decide which fits your lifestyle and budget better.


Size, space, and practicality


Although both models accommodate five passengers and offer Lexus safety features, they differ considerably in footprint and cargo capacity.



  • Exterior footprint and stance: The NX 300 is a compact SUV with a smaller overall size, while the RX 350 is a midsize SUV with a longer wheelbase and wider rear cargo area.

  • Interior space: The RX 350 generally provides more passenger room, especially for rear-seat occupants, and a more spacious feel overall.

  • Cargo capacity: The RX 350 offers notably more cargo space behind and with seats folded compared to the NX 300, which is more compact for everyday errands and urban use.


In short, the RX 350 is the better choice if you need more interior room and cargo flexibility, while the NX 300 suits buyers prioritizing smaller size and urban maneuverability.


Performance, powertrains, and driving dynamics


Engine options and performance targets differ, with the RX 350 delivering more power and a smoother long-distance ride, while the NX 300 emphasizes efficiency and agility in city and light highway driving.



  • NX 300: Typically equipped with a turbocharged 2.0-liter inline-4 engine, producing a robust amount of power for a compact SUV. It is paired with an automatic transmission and offers all-wheel drive as an option in many markets.

  • RX 350: Uses a 2.4-liter turbocharged four-cylinder engine that produces more horsepower and higher torque, contributing to quicker acceleration for a midsize SUV. All-wheel drive is often available or standard on higher trims.

  • Transmission and drivetrain: Both models use a Lexus-supplied automatic gearbox (commonly 8-speed) with available all-wheel drive; the RX 350 tends to feel more refined at highway speeds due to its size and power.


Overall, the RX 350 delivers stronger acceleration and steadier highway performance, while the NX 300 offers adequate power for everyday driving with typically better efficiency.


Interior, technology, and features


Inside the cabin, both SUVs share Lexus design language, but the RX 350 usually provides more space, premium materials, and often larger display options and available comfort features on higher trims.



  • Infotainment and displays: The NX 300 tends to feature Lexus' modern infotainment system with touchscreens sized for the price segment, while the RX 350 often offers larger screen options and enhanced media/navigation capabilities on higher trims.

  • Standard and available features: The RX 350 commonly offers more upscale options (such as higher-grade leather, ventilated seats, and advanced driver aids) as standard or available, reflecting its higher price tier.

  • Safety technology: Both models include Lexus Safety System+ or its latest iteration, but the RX 350 may offer more advanced driver-assistance features or bundle options on premium trims.


For buyers who want maximum luxury and space, the RX 350 is typically the stronger choice. For those who value a refined interior with efficient packaging and lower running costs, the NX 300 remains appealing.


Pricing, efficiency, and ownership costs


Cost of entry and ongoing ownership expenses reflect the size and power differences, along with equipment levels and trim availability.



  • Starting price: The NX 300 usually carries a lower starting price than the RX 350, reflecting its compact footprint and lighter hardware.

  • Fuel economy: The NX 300 generally offers better efficiency due to its smaller engine and lighter weight, though real-world economy varies with driving style and configuration. The RX 350, being larger and more powerful, typically consumes more fuel.

  • Maintenance and depreciation: Both benefit from Lexus reliability, but the RX 350’s higher initial price and greater feature set can influence resale value and total ownership costs in different ways depending on market demand and trim.


In short, if budget and efficiency are top priorities, the NX 300 is typically the more economical choice. If you want more space and premium features with stronger highway performance, the RX 350 justifies its higher price tag for many buyers.


Summary


In comparing the Lexus NX 300 and the Lexus RX 350, think of the NX 300 as a compact, efficient urban SUV, ideal for daily commuting and tight spaces, with lower running costs. The RX 350 is a larger, more powerful midsize SUV that offers more passenger and cargo space, a more luxurious touch, and stronger highway performance, at a higher price. Your choice should hinge on how much interior space you need, how important performance and comfort are to you, and what you’re willing to pay upfront and over time.


Whichever you choose, both models reflect Lexus’s emphasis on refined ride quality, solid safety equipment, and strong reliability. Always verify exact specifications for the model year and market you’re considering, as features and powertrains can vary by region and production run.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.