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What is the difference between the Lexus RX350 and the NX 300?

The RX 350 is the larger, more powerful option with more cargo space, while the NX 300 is the smaller, more efficient and affordable choice. Both deliver Lexus reliability and luxury, but they cater to different buying priorities.

Overview: who should consider each model

Before diving into specifics, it helps to know the core distinction: the RX 350 is aimed at buyers who want a roomy, comfortable two-row SUV with more interior space and a smoother ride on longer trips. The NX 300 targets those who prioritize city-friendly size, better fuel economy, and lower upfront cost, without sacrificing luxury amenities.

Here are the main differences to consider when choosing between the RX 350 and NX 300:

Size and space: RX 350 is the larger vehicle with more cabin and cargo room; NX 300 is more compact and easier to maneuver in tight spaces.

Power and performance: RX 350 typically offers more power and a smoother, quieter ride; NX 300 emphasizes agility and efficiency with a smaller engine setup.

Fuel economy: NX 300 generally delivers better efficiency in everyday driving; RX 350 uses more fuel but prioritizes comfort and power.

Interior and tech: Both share Lexus luxury and safety tech, but the RX 350 often features a roomier rear seat and more upscale options; the NX 300 highlights modern interfaces and compact-cabin practicality.

Price and value: NX 300 starts lower at the showroom, making it a more accessible entry into Lexus luxury; RX 350 starts higher but provides more space and amenities.

In summary, the RX 350 is the roomier, more powerful choice for families and longer trips, while the NX 300 suits urban living and budget-conscious buyers who still want premium features.

Size and practicality

The RX 350 sits in the mid-size, two-row SUV segment, offering more interior volume and cargo space. It’s a better option if you regularly haul people or gear and value rear-seat legroom and a generous luggage area. The NX 300, being smaller and lighter, excels in urban environments where parking and tight turning radii matter, and it still provides comfortable seating for five with usable cargo space for daily use.

Powertrains, performance, and efficiency

Power and how that power feels differ between the two. The RX 350 tends to deliver stronger acceleration and a refinement-focused ride, especially on highways or long commutes. The NX 300 tends to favor nimble handling and quicker responses in city driving, with a focus on better fuel economy. Both SUVs offer all-wheel drive as an option, but neither is designed to be a high-performance vehicle; they are tuned for comfort, efficiency, and everyday practicality.

What to expect from the engines

Engine availability and output vary by model year and trim. In general, the RX 350 uses a turbocharged engine that prioritizes smooth power delivery and a quiet cabin. The NX 300 uses a smaller or hybrid powertrain setup that emphasizes efficiency and responsive city driving. If you’re comparing specific model years, checking the exact horsepower and torque figures is a good idea, but the broader takeaway is that RX 350 emphasizes power and serenity, while NX 300 emphasizes efficiency and agility.

Interior technology and features

Both models share Lexus’s commitment to luxury, safety, and user-friendly tech. The RX 350 typically offers more cabin space and may include upscale seating materials and options like a larger infotainment display or premium audio in higher trims. The NX 300 emphasizes modern tech interfaces and a compact, tech-forward cockpit, with screen sizes and infotainment layouts that favor ease of use in a smaller footprint. Standard safety suites—like Lexus Safety System+—are widely available on both, with more driver-assist options at higher trims.

Pricing, value, and ownership costs

Pricing generally reflects size and capability. The NX 300 starts lower at showroom pricing, appealing to buyers who want premium Lexus luxury at a lower entry point. The RX 350 commands a higher starting price but compensates with greater interior space, insulation, and a more powerful driving experience. Ownership costs—maintenance, insurance, and depreciation—tend to follow market expectations for the two segments, with both models benefiting from Lexus’s reputation for reliability and resale value.

Which one should you buy?

Your decision comes down to priorities. If you need more cargo room, rear-seat comfort, and a more powerful, serene ride for long trips or a growing family, the RX 350 is the stronger pick. If you value compact maneuverability, lower upfront cost, and better daily fuel economy for urban living, the NX 300 is the smarter fit. Test drives of both, focusing on seating comfort, cabin quietness, and tech interfaces, will help you choose based on your actual driving patterns.

Summary

In short, the RX 350 and NX 300 are both premium Lexus SUVs, but they serve different purposes. The RX 350 is the larger, more luxurious, and more capable option with abundant space and power. The NX 300 is the smaller, lighter, and more efficient choice with a lower price point and easier urban usability. Your best pick depends on whether you prioritize space and power or compact practicality and efficiency.

Which Lexus is better, NX or RX?

The "better" Lexus depends on your priorities: the RX is a mid-size SUV better for more space, power, and families, while the NX is a compact SUV better for city driving, fuel efficiency, and a lower price point. Both offer hybrid and gas options, similar technology, and high reliability.
This video compares the Lexus RX and NX and discusses which model is right for you: 1mLSFTYouTube · Oct 10, 2025

Feature	Lexus RX	Lexus NX
Size	Mid-size SUV (longer, wider, taller)	Compact SUV
Space	More interior legroom, headroom, and cargo space; better for families	More compact and nimble; still comparable cargo capacity
Performance	More powerful engine options available	Offers a balance of power and fuel economy
Fuel Efficiency	Slightly lower EPA-estimated MPG for base engine	Slightly higher EPA-estimated MPG for base engine
Price	Higher initial cost	Lower initial cost
Long-Term Value	Potentially better depreciation resistance and resale value	More economical for urban commuting
Technology	Both have similar infotainment and safety systems, but the RX comes standard with a larger 14-inch touchscreen and offers available Traffic Jam Assist.	Lower trims have a smaller screen, and Traffic Jam Assist is not available.

What is the difference between nx 300 and RX 350?

The main differences are that the Lexus NX is a more compact SUV, while the RX is a larger, midsize SUV with more interior space and a more powerful standard engine. The RX also has a higher price point and offers some features, like Traffic Jam Assist, as an option that the NX does not.
This video highlights the interior differences between the Lexus RX and NX, focusing on space and luxury features: 59sPerformance LexusYouTube · Aug 17, 2024
This video provides a visual comparison of the exterior and interior designs of the new Lexus NX and RX: 1mPerformance LexusYouTube · Feb 5, 2023
You can watch this video to compare the interior quality and features of the Lexus NX and RX: 1mLife with SondurenYouTube · Jul 28, 2023

Feature	Lexus NX 300	Lexus RX 350
Size	Compact SUV	Midsize SUV, longer and wider
Engine	Standard 2.0L Turbo I4 (235 hp)	Standard 3.5L V6 (295 hp)
Performance	Faster 0-60 mph acceleration in some comparisons	More overall horsepower
Fuel Economy	Higher MPG for the base gasoline model	Lower MPG for the base gasoline model
Interior Space	Less rear legroom and cargo space	More legroom, cargo space, and a generally more spacious feel
Price	Lower starting price	Higher starting price
Standard Safety	Standard Lexus Safety System suite with many features	Standard Lexus Safety System suite with many features
Unique Features	Offers standard features like dual-zone climate control	Offers optional features like Traffic Jam Assist, multi-zone climate control, and a larger available infotainment screen

Why is RX more expensive than NX?

Why is RX more expensive than NX? The RX commands a premium because of its greater size, more powerful engine options, additional luxury touches, and higher towing capacity compared to the NX.

What are the nx 300's common problems?

The owner comments describe problems respondents experienced with this vehicle.

Brakes.
Noises/Leaks.
Engine Major.
Climate System.
Electrical Accessories.
In-car Electronics.
Drive System.
Suspension/Steering.

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.