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What is the fuel consumption of the Lexus RX 450h hybrid?

In the United States, the RX 450h hybrid typically achieves roughly 29–34 miles per gallon (mpg) combined, depending on year, drivetrain, and wheel size.


This article explains how those figures vary across generations, what factors influence real-world mileage, and how to find the exact EPA rating for a given model year and trim.


Fuel economy by generation


Note: EPA estimates vary by market and option packages; the ranges below reflect typical U.S. ratings for standard configurations.


First generation (2009–2015)


Early RX 450h models used a hybrid system paired with a V6, delivering mileage that generally lands in the high 20s to around 30 mpg combined, with variations based on drivetrain and wheels.



  • Typical EPA combined mpg: about 28–30 mpg

  • City mpg: roughly in the high 20s; highway mpg: around 30 mpg in many configurations


Overall, the first-generation hybrid offered competitive efficiency for its time, though numbers varied with wheel choice and options.


Second generation: RX 450h L (2016–2022)


The RX 450h L added a longer wheelbase and a larger battery in some trims, which generally kept overall fuel economy in the high 20s to low 30s mpg combined, depending on drivetrain and tires.



  • Typical EPA combined mpg: about 28–31 mpg

  • AWD versions typically on the lower end of the range


The hybrid system remained efficient, but the added weight and aerodynamics of the extended model influenced efficiency modestly.


Current generation: RX 450h / RX 450h+ (2023–present)


In the latest generation, the hybrid lineup aims for improved efficiency through updated powertrains and weight management. EPA estimates generally fall in the upper 20s to mid-30s mpg combined, with FWD versions often achieving higher numbers than AWD, and wheel/tire choices affecting the result.



  • Typical EPA combined mpg: about 29–34 mpg

  • FWD vs AWD: FWD higher on average by a few mpg


Precise numbers vary by model year, trim, and wheel/tire package, so check the official EPA label for the exact figure.


These ranges illustrate how hybrid fuel economy changes across generations, and why exact numbers depend on your chosen configuration.


Factors that influence real-world fuel economy


Actual mileage can diverge from EPA estimates based on several conditions and habits. The following factors commonly influence RX 450h efficiency in daily driving.



  • Driving style: quick acceleration and heavy braking reduce mpg.

  • Terrain and climate: hilly driving, towing, and extreme temperatures can impact battery usage and engine efficiency.

  • Wheel size and tires: larger wheels and low-rolling-resistance tires affect rolling resistance and aerodynamics.

  • Trip length and traffic conditions: frequent short trips prevent the hybrid system from optimizing energy recovery.

  • Maintenance and equipment: properly inflated tires, clean air filters, and up-to-date maintenance help sustain efficiency.


To maximize efficiency, drive smoothly, keep tires inflated to recommended pressures, and plan routes to minimize stops.


Summary


The Lexus RX 450h hybrid offers competitive fuel economy for a mid-size SUV, with typical combined mpg in the upper 20s to mid-30s depending on year and configuration. For precise numbers, review the EPA fuel economy label for your specific model year and trim, and consider how your driving conditions will affect real-world mileage.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.