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How many miles can a 2007 Lexus RX 350 last?

With proper maintenance, a 2007 Lexus RX 350 can routinely reach 250,000 miles or more; many owners report 200k–300k miles, and a few surpass 300k. The engine in this model is the 3.5-liter V6 (2GR-FE) with a timing chain, a design that generally supports long life when cared for.


This article examines how far a 2007 RX 350 can go, the factors that influence longevity, and practical steps owners can take to maximize the vehicle’s lifespan.


What factors influence how long it lasts


Longevity in the RX 350 is shaped by a combination of maintenance, driving style, and environmental conditions. Below are the most impactful factors:



  • Maintenance history and adherence to the factory service schedule

  • Driving conditions (highway cruising versus frequent short trips and stop-and-go driving)

  • Climate, road salt exposure, and overall protection against corrosion

  • Quality of repairs and the availability of good replacement parts

  • Timely addressing of warning signs, leaks, or unusual noises

  • Overall wear on major components such as the suspension, drivetrain, and cooling system


In short, consistent care and sensible use are the best predictors of whether the RX 350 will reach high mileage.


Real-world mileage milestones


Owner reports and automotive forums highlight several common mileposts for the 2007 RX 350, illustrating what diligent maintenance can achieve:



  • 200,000 miles: A widely observed milestone for well-kept examples

  • 250,000 miles: Not uncommon with routine service and careful driving

  • 300,000 miles and beyond: Less common, but documented by owners who stay on top of maintenance


These milestones reflect the potential path many RX 350s follow when cared for over the long term.


Maintenance practices that maximize life


To push the 2007 RX 350 toward the upper end of its expected lifespan, prioritize these maintenance practices and habits:



  • Follow the owner’s manual for maintenance intervals, and use the recommended oil type and change cadence (often 5,000 miles with conventional oil or longer intervals with synthetic oil, depending on driving conditions)

  • Regularly inspect and service the cooling system, including coolant replacement and hoses

  • Keep transmission fluid in good condition and follow the service schedule; address leaks or shifting issues promptly

  • Monitor and replace wear items before they fail (brakes, tires, suspension components)

  • Schedule timely inspections for leaks, hoses, belts (the 2GR-FE uses a timing chain, but tensioners and related components should be checked periodically)

  • Maintain rust protection and underbody care if the vehicle lives in salty or humid environments

  • Keep detailed service records and address any recalls or service campaigns


Sticking to these routines and addressing problems early can significantly extend the RX 350’s life.


Summary: A well-maintained 2007 Lexus RX 350 can reliably reach 250,000 miles and often beyond, with 300,000 miles achievable for many owners who stay on top of service, use quality parts, and drive sensibly.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.