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How many miles per gallon does the is350 get?

The Lexus IS350 typically achieves in the low- to mid-20s miles per gallon combined. Real-world numbers vary by model year, drivetrain (rear-wheel drive vs. all-wheel drive), and whether the vehicle uses a 6-speed or 8-speed automatic transmission.


This article explains how fuel economy for the IS350 has varied across generations and configurations, and how to determine the exact figure for a specific car or model year.


Typical EPA ranges by configuration


These ranges reflect common EPA estimates for IS350 models equipped with the 3.5-liter V6 and an automatic transmission. Individual vehicles can differ based on tires, maintenance, and driving style.



  • Rear-wheel-drive IS350: combined mpg commonly in the low- to mid-20s (roughly 22–25 mpg in many years).

  • All-wheel-drive IS350: combined mpg commonly in the low 20s (roughly 20–23 mpg in many years).


In short, plan for about 22–25 mpg for RWD versions and about 20–23 mpg for AWD versions on average.


How mpg varied by generation


The IS350 appeared in two major generation windows. Earlier models (approximately 2006–2013) with a 3.5L V6 and automatic transmissions typically posted strong highway numbers, while later generations (approximately 2014–2020) with refined automatics improved highway efficiency but kept city mileage modest due to weight and performance.



  • First generation (approx. 2006–2013): EPA estimates typically placed combined mpg in the mid-20s for RWD, with highway mileage often higher than city.

  • Second generation (approx. 2014–2020): Combined mpg typically in the low-to-mid 20s, with RWD slightly more efficient than AWD.


As always, exact figures depend on the year, drivetrain, and options; the EPA label on the door jamb provides the official numbers for a given vehicle.


City vs highway dynamics


IS350s generally deliver better highway mileage than city driving. Highway figures can approach the higher end of the range for some configurations, while city ratings tend to be lower. Real-world driving often lands in the low-to-mid 20s combined, depending on traffic and driving style.


Tips to maximize mpg


To squeeze more miles per gallon from an IS350, maintain proper tire inflation, perform regular maintenance, remove excess weight, and drive with smooth acceleration and steady speeds on highway stretches.


Why exact numbers matter


Because the IS350 was produced across multiple model years and configurations, exact EPA estimates vary. If you want the precise figure for a specific IS350 (year, drivetrain, and transmission), provide those details and I’ll pull the exact EPA rating or guide you to the official spec sheet.


Summary


In short, the IS350’s MPG sits in the low- to mid-20s on average, with rear-drive versions typically a bit more efficient than all-wheel-drive ones. For precise figures, check the EPA rating for the exact model year and configuration you’re considering, or share those details and I’ll fetch the exact numbers.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.