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What is the difference between IS 300 and is 350?

In brief, the IS 350 is the more powerful, V6-powered option, while the IS 300 uses a turbocharged four-cylinder for brisk acceleration and better efficiency. Both share Lexus’s reputation for luxury, build quality, and technology, but they appeal to different buyers based on performance needs and budget.


What these two models are and how they fit in the lineup


The Lexus IS sedan line centers on compact luxury with two main powertrain choices in recent years: the IS 300, which uses a turbocharged four-cylinder, and the IS 350, which uses a larger naturally aspirated V6. Availability and exact specifications can vary by market and model year, but the broad distinction remains the same: one emphasizes efficiency and agility, the other emphasizes stronger acceleration and a more muscular feel.


Powertrain and performance


The core differences live under the hood. The following outlines summarize how the two engines translate to on-road behavior.


IS 300 (2.0L turbocharged inline-4)



  • Engine: 2.0-liter turbocharged four-cylinder

  • Power: roughly 241 horsepower

  • Torque: around 258 lb-ft

  • Transmission: 8-speed automatic

  • Drivetrain options: rear-wheel drive (RWD) standard; all-wheel drive (AWD) available


The turbo-four in the IS 300 delivers brisk, responsive acceleration with stronger efficiency than the V6 option, and AWD availability helps in adverse weather. Its character is more about everyday liveliness and agility than raw straight-line speed.


IS 350 (3.5L V6)



  • Engine: 3.5-liter V6

  • Power: about 311 horsepower

  • Torque: around 280 lb-ft

  • Transmission: 8-speed automatic

  • Drivetrain options: rear-wheel drive (RWD) and AWD available


With more power and a broader torque curve, the IS 350 accelerates faster and delivers a more emphatic driving experience, especially at higher speeds. It’s typically preferred by buyers seeking stronger performance and a more engaging soundtrack.


Efficiency, handling and daily use


Fuel economy, ride quality, and handling balance differ between the two models, reflecting their pacesetter purposes. The IS 300’s turbocharged four generally yields better city fuel economy and nimble response, while the IS 350’s V6 prioritizes confident highway passing power and a more energetic feel on winding roads. Both share Lexus’s refined ride, good interior noise isolation, and chassis that favor comfort with a sporty edge.



  • IS 300 tends to deliver better efficiency and lighter handling feel in daily driving

  • IS 350 delivers stronger performance and a more muscular acceleration profile


In everyday use, your choice may come down to whether you want sharper fuel economy and a nimble feel (IS 300) or stronger straight-line performance and a more premium powertrain experience (IS 350).


Trims, features and pricing


Both models share a core cabin design, technology suite, and optional equipment, but the IS 350 usually sits higher in price and availability of sport-oriented features. Features and packages can vary by model year and region, including leather upholstery, driver-assistance tech, and infotainment hardware.


What you get by trim level



  • IS 300: base hardware with optional upgrades; newer models commonly include smartphone integration and advanced safety tech

  • IS 350: extra power and usually more standard or available sport-oriented equipment; upgraded brakes and suspension tuning are common on sport trims


Concluding paragraph: If budget and efficiency are priorities, the IS 300 offers compelling value with strong performance. If you want more power and a sportier driving character, the IS 350 is the better fit and tends to command a higher price.


Which one is right for you? A quick guide


Choose the IS 300 if you value daily usability, better fuel economy, and a more approachable entry point into Lexus sport-luxury. Choose the IS 350 if you crave stronger acceleration, a more aggressive powertrain feel, and you’re willing to pay more for the performance edge. Always consider test drives to evaluate how the engine sound, throttle response, and ride quality match your preferences.


Market variations and model years


Engine outputs, trim availability, and even name usage can differ by country and model year. In some markets, the IS line used different designations or powertrain combinations, and Lexus has updated tech and efficiency targets across generations. For the most accurate comparison, verify the exact specifications for the specific year and region you’re considering.


Summary


The Lexus IS 300 and IS 350 sit at the crossroads of efficiency and performance within Lexus’s compact-luxury sedan lineup. The IS 300 relies on a 2.0-liter turbocharged four-cylinder for spirited, efficient driving and versatile weather capability with AWD options. The IS 350 uses a 3.5-liter V6 to deliver stronger acceleration, a more aggressive character, and a higher price tag. Both share upscale interiors, refined ride quality, and modern technology; the choice comes down to whether you prize everyday efficiency and agility (IS 300) or outright performance and presence (IS 350).

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.