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Is the Lexus GS 350 good on gas?

In short, the GS 350 delivers fuel economy in the low- to mid-20s mpg, which is typical for a non-hybrid, V6-powered midsize luxury sedan of its era. It isn’t a fuel-sipper, but it provides respectable efficiency for a performance-forward luxury car.


The Lexus GS 350 uses a 3.5-liter V6 paired with an automatic transmission, with rear-wheel drive as standard and all-wheel drive optional. Since production ended after the 2020 model year, official efficiency figures come from EPA data collected over its run and can vary by year, drivetrain, and tire setup. This article reviews official numbers, real-world results, and practical tips to maximize mpg for this model.


Official fuel economy for common GS 350 configurations


EPA ratings provide a baseline for how efficiently the GS 350 uses fuel. Figures can vary by year, drivetrain, and options, but the numbers below reflect typical configurations owners encounter.



  • Lexus GS 350 with rear-wheel drive (3.5L V6): about 20 mpg city / 28 mpg highway / around 23 mpg combined.

  • Lexus GS 350 with all-wheel drive (3.5L V6): about 19 mpg city / 26 mpg highway / around 22 mpg combined.


Note: Real-world results vary with year, trim, tires, and maintenance. Always check the specific EPA rating for a given model year when evaluating a used GS 350.


Real-world performance and factors that influence efficiency


In everyday driving, the GS 350’s economy can swing based on how and where you drive. Owners often report mpg in the low- to mid-20s in mixed use, with higher numbers on steady highway trips and lower numbers during urban, stop-and-go patterns.



  • Driving style: Aggressive acceleration, quick throttle bursts, and frequent braking lower mpg; smooth, gradual acceleration and steady speeds improve it.

  • Trip type: Highway-only trips tend to yield higher mpg; city commutes with frequent stops reduces mpg.

  • Tire and load conditions: Underinflated tires and heavier loads reduce efficiency; proper tire inflation and reduced weight help.

  • Age and maintenance: A worn engine, dirty air filters, and misfires can degrade mpg; routine maintenance keeps it closer to EPA estimates.

  • Climate control use: Air conditioning in hot weather can lower mpg, especially at city speeds; using eco mode or preconditioning can help.


Understand that the GS 350 is not a hybrid, so its mpg will be consistently lower than fuel-efficient four-cylinders or hybrid models. Realistic expectations align with mid-20s mpg in mixed driving for most owners, with higher highway numbers and lower urban numbers.


Tips to maximize fuel economy in the GS 350


Small, practical changes can help you maximize efficiency without sacrificing performance or comfort. Implement these strategies to squeeze more miles per gallon from your GS 350.



  • Keep tires properly inflated to the manufacturer’s recommended pressure; underinflated tires can reduce mpg by several percent.

  • Drive with gradual acceleration, anticipate stops, and use planned, smooth braking to maintain momentum.

  • Limit roof racks and heavy accessories when not in use, since added drag lowers highway mpg.

  • Follow the maintenance schedule, replace air filters, and ensure spark plugs and oxygen sensors are in good condition.

  • Use eco mode if available, and precondition the cabin while the car is parked to minimize driving with AC on high from the start.


Even with these steps, the GS 350’s focus remains on delivering strong performance and luxury refinement rather than maximizing miles-per-gallon, but sensible driving can provide a meaningful boost.


Summary


The Lexus GS 350 offers respectable fuel efficiency for its class, with typical combined mpg in the low- to mid-20s depending on drivetrain and year. It’s not a fuel-economy leader, but it balances power and luxury with workable real-world efficiency. If ultimate fuel savings are a priority, consider more modern four-cylinder or hybrid options; if you want V6 refinement and performance, the GS 350 remains a solid choice with reasonable gas mileage for daily driving.

Is the Lexus 350 good on gas?


Drivers in the 2022 Lexus RX 350 will get an estimated 27 miles per gallon when driving on the highway and 20 miles per gallon around the town to make a combined 23mpg.



Is the Lexus IS 350 fuel efficient?


The 2022 IS has the option to equip 1 of 4 different engines with its own unique gas mileage. The available IS 350 F Sport features fuel efficiency of 20 city MPG, 28mpg on the highway, and 22 miles per gallon combined.



How many miles per gallon does a Lexus GS 350 get?


The GS 350 gets an EPA-estimated 19/26/21 mpg city/highway/combined with all-wheel drive. With rear-wheel drive, mileage is rated 19/29/23 mpg.



Is the GS 350 expensive to maintain?


The estimated cost to maintain and repair a Lexus GS350 ranges from $105 to $3274, with an average of $413.


Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.