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Is the Lexus RX 350 fuel efficient?

Yes—the RX 350 offers respectable fuel economy for a mid-size luxury SUV, but the hybrid RX 350h is noticeably more efficient.


To understand whether the RX 350 is fuel efficient, consider the engine and drivetrain, the model year, and how you drive. This article explains the differences between the gasoline RX 350 and the hybrid RX 350h, how EPA ratings translate to real-world use, and how it stacks up against similar crossovers.


How the RX 350 achieves its efficiency


The RX 350 uses a 3.5-liter V6 paired with an eight-speed automatic transmission. In practice, fuel economy depends on whether the SUV is equipped with front-wheel drive or all-wheel drive, the model year’s tweaks, and how you drive. Gasoline versions typically deliver fuel economy in the low-to-mid 20s in city driving and in the high 20s to low 30s on highways, with combined figures generally landing in the mid-20s to upper-20s depending on configuration.


Powertrain and design factors


Key design choices that influence efficiency include engine displacement, the number of gears, drive configuration (FWD vs. AWD), weight, and aerodynamics. Lexus has tuned the RX 350 for a balance between performance and efficiency, but it remains a naturally aspirated V6-powered vehicle rather than a small-turbo or plug-in design.


The following factors frequently influence actual fuel economy in daily use:



  • Drivetrain choice (FWD typically cleaner than AWD)

  • Maintenance and tire condition (proper inflation and service)

  • Driving style (steady speed vs. rapid acceleration and hard braking)

  • Load and cargo height (roof racks and heavy payload raise drag)

  • Road conditions and terrain (hilly vs. flat terrain)


In practice, staying within the EPA estimates depends on maintaining optimal conditions and adopting efficient driving habits.


Gas vs hybrid: what to expect


The hybrid RX 350h uses electric assistance and a continuously variable transmission (CVT) to boost efficiency, especially in city driving where electric motors can operate more often. Compared with the gasoline RX 350, the RX 350h typically delivers a meaningful boost in combined fuel economy, often landing in the mid- to upper-30s mpg range depending on the model year and drivetrain. Real-world results can vary, but the hybrid generally offers a clear advantage for drivers who cover a lot of city miles or longer daily commutes.


For those evaluating overall cost of ownership, it’s important to weigh the higher upfront price of the hybrid against expected fuel savings, potential tax incentives, and your typical driving patterns. The RX lineup also includes other powertrain options in certain years and markets, but the most direct comparison remains gasoline RX 350 versus hybrid RX 350h.


These two configurations illustrate how the RX family addresses efficiency differently: the gasoline RX 350 prioritizes performance and refinement, while the RX 350h emphasizes efficiency through hybridization. Your choice will depend on your daily driving needs and fuel-price expectations.


Tips to maximize fuel economy in daily use


Whether you own the gasoline RX 350 or the hybrid, small changes can improve real-world fuel economy. The following practices are practical and widely recommended by owners and reviewers:



  • Aim for smooth acceleration and steady speeds, especially on highways.

  • Keep tires inflated to the manufacturer’s recommended pressure and rotate them as advised.

  • Reduce unnecessary weight and avoid roof racks or carriers that add drag when not in use.

  • Perform regular maintenance, including spark plugs, air filters, and engine oil changes per the owner's manual.


In practice, combining efficient driving with well-maintained systems can help you approach or exceed EPA estimates over time.


Summary


The Lexus RX 350 delivers respectable fuel economy for a mid-size luxury SUV, especially in everyday driving conditions. If maximizing efficiency is a priority, the RX 350h hybrid offers a clear advantage with better combined mileage and typically stronger city performance. Real-world results vary by model year, drivetrain, and driving style, so check the EPA ratings for your specific configuration and plan accordingly. For many buyers, the trade-off between comfort, performance, and efficiency will guide the right choice within the RX lineup.

Is the Lexus RX 350 a woman's car?


Even though women love this SUV, it's a good buy for men as well, assuming they can put aside their macho tendencies.



What are the disadvantages of a Lexus RX 350?


Early Lexus RX 350 releases experienced steering issues, notably power steering fluid leaks from the rack and pinion system. Not only is this a massive safety hazard – it can also be costly to repair. Unfortunately, the problem is hard to predict and can also affect vehicles with fewer than 100,000 miles on the clock.



What year to avoid RX 350?


Model Years You Might Want to Skip
While the RX 350 is generally a solid vehicle, a few model years have seen more complaints than others. It's wise to be cautious with the 2007, 2008, 2010, 2016, and 2017 models.



Is the Lexus RX 350 good on gas?


Drivers in the 2022 Lexus RX 350 will get an estimated 27 miles per gallon when driving on the highway and 20 miles per gallon around the town to make a combined 23mpg.


Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.