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What is the mpg on a 1999 Ford E-350?

On a 1999 Ford E-350, fuel economy varies by engine and configuration. Gasoline models generally deliver roughly 12–16 miles per gallon (mpg) in mixed driving, while diesel-equipped versions tend to achieve mid-teens to around 20 mpg on highway.


Engine options and their typical mpg ranges


The 1999 E-350 was offered with several powertrains. Gasoline setups included a 4.2-liter V6 and a 5.4-liter V8, while a diesel option (7.3-liter IDI/Power Stroke) was available on heavier configurations. Because payload, transmission, and body configuration vary (cargo vs passenger van), actual mpg can differ significantly.


Estimated mpg ranges by engine configuration (rough averages based on era data and owner reports):



  • Gasoline 4.2L V6: typically about 12–16 mpg combined.

  • Gasoline 5.4L V8: typically about 11–15 mpg combined.

  • Diesel 7.3L IDI/Power Stroke: typically about 15–20 mpg combined, with highway figures often higher than city driving.


Note: Actual fuel economy will vary with load, terrain, maintenance, and driving conditions.


Factors that affect mpg on the 1999 E-350


Several factors can dramatically affect real-world mpg for these vans. Payload, tire size and inflation, aerodynamics from cargo loads, transmission type, drivetrain configuration, and driving habits all play a role.



  • Payload and towing: Heavier loads increase fuel use and reduce efficiency.

  • Maintenance and condition: Worn spark plugs, dirty air filters, or a clogged fuel system can lower mpg.

  • Tire choice and pressure: Underinflated tires raise rolling resistance and decrease economy.

  • Driving style: Aggressive acceleration and frequent idling in traffic reduce mpg.

  • Terrain and climate: Hills and extreme temperatures can affect performance and efficiency.


In practice, if you're assessing a 1999 E-350, check the specific vehicle's MPG estimates from its window sticker or owner reports for the exact configuration, and expect a range of real-world results around the posted ranges above.


Practical tips to maximize mpg


To maximize fuel efficiency from a 1999 E-350, consider these maintenance and driving practices:



  • Keep the drivetrain well-maintained with regular tune-ups, clean air filters, and proper fuel system maintenance.

  • Maintain correct tire pressure and use appropriate tires to minimize rolling resistance.

  • Limit payload where possible and distribute weight to improve efficiency.

  • Avoid prolonged idling and plan efficient routes to reduce stop-and-go driving.

  • Use cruise control on highways and drive at steady, moderate speeds to optimize consumption.


While these classic vans aren’t known for standout fuel economy, proper maintenance and mindful loading can help you achieve the best possible mileage for a 1999 E-350.


Summary


The 1999 Ford E-350’s fuel economy depends heavily on engine choice, payload, and driving conditions. Gasoline configurations typically fall in the low-to-mid-teens mpg, while diesel variants can push toward the higher end of the 15–20 mpg range with favorable highway conditions. Real-world numbers vary, so verify the specific configuration and performance data for the exact vehicle and set expectations accordingly.

Kevin's Auto

Kevin Bennett

Company Owner

Kevin Bennet is the founder and owner of Kevin's Autos, a leading automotive service provider in Australia. With a deep commitment to customer satisfaction and years of industry expertise, Kevin uses his blog to answer the most common questions posed by his customers. From maintenance tips to troubleshooting advice, Kevin's articles are designed to empower drivers with the knowledge they need to keep their vehicles running smoothly and safely.